Infectious agents and inflammatory processes contribute to a range of heart diseases, some of which can lead to long-term cardiac complications if not treated adequately. Myocarditis, an inflammation of the heart muscle, and infective endocarditis, an infection of the heart valves, are among the most concerning infectious causes of heart disease. These conditions often present with nonspecific symptoms, making early diagnosis a challenge. Inflammatory responses, whether triggered by infections or autoimmune diseases, can disrupt the normal function of the heart, causing arrhythmias, heart failure, or even sudden cardiac death. Managing infections and inflammatory heart diseases typically requires a combination of antimicrobial treatments and anti-inflammatory medications, along with close monitoring to prevent further heart damage. Timely intervention can significantly improve prognosis and prevent the development of chronic heart conditions.