Acute Coronary Syndrome (ACS) is a term used to describe a range of conditions associated with sudden, reduced blood flow to the heart muscle. It encompasses a spectrum of coronary artery diseases, including unstable angina and myocardial infarction (heart attack). ACS typically occurs when there is a rupture of an atherosclerotic plaque in a coronary artery, leading to the formation of a blood clot that partially or completely blocks blood flow to the heart. The hallmark symptoms of ACS include chest pain or discomfort, often radiating to the arms, neck, jaw, or back. Additional symptoms might involve difficulty breathing, feelings of nausea, and experiencing cold sweats. Recognizing and promptly treating ACS is critical, as it can lead to significant damage to the heart muscle, resulting in long-term complications or even death. Diagnosis involves a combination of clinical assessment, electrocardiograms (ECGs), blood tests to measure cardiac biomarkers and imaging studies. Immediate interventions, such as administering antiplatelet medications, nitroglycerin, and anticoagulants, aim to restore blood flow to the heart. In certain cases, procedures like angioplasty and stent placement or coronary artery bypass surgery may be necessary. Long-term management involves lifestyle modifications, medications, and cardiac rehabilitation to reduce the risk of recurrent events. ACS requires urgent medical attention, and individuals experiencing symptoms should seek immediate help to improve outcomes and prevent further damage to the heart.